Chemistry and biochemistry of (-)-hydroxycitric acid from Garcinia - PubMed

(-)-Hydroxycitric acid [(-)-HCA] is the principal acid of fruit rinds of Garcinia cambogia, Garcinia indica, and Garcinia atroviridis. (-)-HCA was shown to be a potent inhibitor of ATP citrate lyase (EC 4.1.3.8), which catalyzes the extramitochondrial cleavage of citrate to oxaloacetate and acetyl-C …分類：pmid:11754536, doi:10.1021/jf010753k, Review, B S Jena, G K Jayaprakasha, K K Sakariah, Animals, Anti-Obesity Agents / chemistry, Anti-Obesity Agents / metabolism, Anti-Obesity Agents / pharmacology, Citrates / chemistry*, Citrates / metabolism*, Citrates / pharmacology, Clusiaceae / chemistry*, Energy Intake / drug effects, Enzyme Inhibitors / chemistry, Enzyme Inhibitors / metabolism, Enzyme Inhibitors / pharmacology, Fruit / chemistry, Humans, Lipid Metabolism*, Weight Loss, PubMed Abstract, NIH, NLM, NCBI, National Institutes of Health, National Center for Biotechnology Information, National Library of Medicine, MEDLINE...