Phytosterols protect against diet-induced hypertriglyceridemia in Syrian golden hamsters - PubMed

Study results suggest that dietary PS are protective against diet-induced hypertriglyceridemia, likely through multiple mechanisms that involve modulation of intestinal fatty acid metabolism and a reduction in hepatic lipogenesis.分類：pmid:24393244, PMC3896966, doi:10.1186/1476-511X-13-5, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't, Todd C Rideout, Vanu Ramprasath, Peter J H Jones, Animals, Anticholesteremic Agents / pharmacology*, Anticholesteremic Agents / therapeutic use, Azetidines / pharmacology, Azetidines / therapeutic use, Cholesterol, HDL / blood, Cricetinae, Diet, High-Fat / adverse effects, Drug Evaluation, Preclinical, Ezetimibe, Fatty Acids / metabolism, Gene Expression / drug effects, Hypertriglyceridemia / blood, Hypertriglyceridemia / drug therapy*, Hypertriglyceridemia / etiology, Intestinal Absorption / drug effects, Intestine, Small / drug effects, Intestine, Small / metabolism, Lipogenesis, Liver / drug effects, Liver / metabolism, Male, Mesocricetus, Phytosterols / pharmacology*, Phytosterols / therapeutic use, RNA, Messenger / genetics, RNA, Messenger / metabolism, Sterol Regulatory Element Binding Protein 1 / genetics, Sterol Regulatory Element Binding Protein 1 / metabolism, PubMed Abstract, NIH, NLM, NCBI, National Institutes of Health, National Center for Biotechnology Information, National Library of Medicine, MEDLINE...