A randomized, crossover, head-to-head comparison of eicosapentaenoic acid and docosahexaenoic acid supplementation to reduce inflammation markers in men and women: the Comparing EPA to DHA (ComparED) Study - PubMed

DHA is more effective than EPA in modulating specific markers of inflammation as well as blood lipids. Additional studies are needed to determine the effect of a long-term DHA supplementation per se on cardiovascular disease risk. This trial was registered at clinicaltrials.gov as NCT01810003.分類：pmid:27281302, doi:10.3945/ajcn.116.131896, Randomized Controlled Trial, Janie Allaire, Patrick Couture, Benoît Lamarche, Adiponectin / blood*, Adult, Aged, Biomarkers / blood, C-Reactive Protein / metabolism*, Cholesterol / blood, Cross-Over Studies, Cytokines / blood*, Dietary Supplements*, Docosahexaenoic Acids / blood, Docosahexaenoic Acids / pharmacology, Docosahexaenoic Acids / therapeutic use*, Double-Blind Method, Eicosapentaenoic Acid / blood, Eicosapentaenoic Acid / pharmacology, Eicosapentaenoic Acid / therapeutic use*, Female, Humans, Inflammation / blood, Inflammation / drug therapy*, Interleukin-18 / blood, Male, Middle Aged, Triglycerides / blood, Tumor Necrosis Factor-alpha / blood, PubMed Abstract, NIH, NLM, NCBI, National Institutes of Health, National Center for Biotechnology Information, National Library of Medicine, MEDLINE...