Dietary Fiber Confers Protection against Flu by Shaping Ly6c- Patrolling Monocyte Hematopoiesis and CD8+ T Cell Metabolism - PubMed

Dietary fiber protects against chronic inflammatory diseases by dampening immune responses through short-chain fatty acids (SCFAs). Here we examined the effect of dietary fiber in viral infection, where the anti-inflammatory properties of SCFAs in principle could prevent protective immunity. Instead …分類：pmid:29768180, doi:10.1016/j.immuni.2018.04.022, Research Support, Non-U.S. Gov't, Aurélien Trompette, Eva S Gollwitzer, Benjamin J Marsland, Adaptive Immunity / drug effects, Adaptive Immunity / immunology, Animals, Antigens, Ly / immunology*, CD8-Positive T-Lymphocytes / immunology*, CD8-Positive T-Lymphocytes / metabolism, Dietary Fiber / administration & dosage, Dietary Fiber / pharmacology*, Fatty Acids, Volatile / immunology, Fatty Acids, Volatile / metabolism, Hematopoiesis / drug effects, Hematopoiesis / immunology*, Humans, Immunity, Innate / drug effects, Immunity, Innate / immunology, Mice, Inbred BALB C, Mice, Inbred C57BL, Mice, Knockout, Monocytes / drug effects, Monocytes / immunology*, Monocytes / metabolism, Orthomyxoviridae Infections / immunology*, Protective Agents / administration & dosage, Protective Agents / pharmacology, PubMed Abstract, NIH, NLM, NCBI, National Institutes of Health, National Center for Biotechnology Information, National Library of Medicine, MEDLINE...